- 1.Patients with upper airway disease, such as rhinitis and rhinosinusitis, should have a higher prevalence of lower respiratory diseases, such as asthma; the corollary, increased prevalence of upper respiratory disease among patients with lower respiratory diseases, also should be present.
- 2.Interrelated pathophysiologic mechanisms between upper and lower airway diseases should exist to explain the interaction of these two disease processes.
- 3.Treatment of one portion of the unified airway should improve symptoms in a separate portion of the respiratory system.
- Asthma and the unified airway.Otolaryngol Head Neck Surg. 2007; 136: S75-S106