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Unified Airway Disease

Examining Prevalence and Treatment of Upper Airway Eosinophilic Disease with Comorbid Asthma
Published:October 17, 2022DOI:https://doi.org/10.1016/j.otc.2022.09.005

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      References

        • Ramakrishnan J.B.
        • Kingdom T.T.
        • Ramakrishnan V.R.
        Allergic rhinitis and chronic rhinosinusitis: their impact on lower airways.
        Immunol Allergy Clin N Am. 2013; 33: 45-60
        • Bachert C.
        • Vignola A.M.
        • Gevaert P.
        • et al.
        Allergic rhinitis, rhinosinusitis, and asthma: one airway disease.
        Immunol Allergy Clin N Am. 2004; 24: 19-43
        • Grossman J.
        One airway, one disease.
        Chest. 1997; 111: 11S-16S
        • Krouse J.H.
        The unified airway.
        Facial Plast Surg Clin North Am. 2012; 20: 55-60
        • Orlandi R.R.
        • Kingdom T.T.
        • Smith T.L.
        • et al.
        International consensus statement on allergy and rhinology: rhinosinusitis 2021.
        Int Forum Allergy Rhinol. 2021; 11: 213-739
        • Leynaert B.
        • Neukirch F.
        • Demoly P.
        • et al.
        Epidemiologic evidence for asthma and rhinitis comorbidity.
        J Allergy Clin Immunol. 2000; 106: S201-S205
        • Thomas M.
        Allergic rhinitis: evidence for impact on asthma.
        BMC Pulm Med. 2006; 6: S4
        • Brozek J.L.
        • Bousquet J.
        • Agache I.
        • et al.
        Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines-2016 revision.
        J Allergy Clin Immunol. 2017; 140: 950-958
        • Linneberg A.
        • Henrik Nielsen N.
        • Frolund L.
        • et al.
        The link between allergic rhinitis and allergic asthma: a prospective population-based study. The Copenhagen Allergy Study.
        Allergy. 2002; 57: 1048-1052
        • Guerra S.
        • Sherrill D.L.
        • Martinez F.D.
        • et al.
        Rhinitis as an independent risk factor for adult-onset asthma.
        J Allergy Clin Immunol. 2002; 109: 419-425
        • Plaschke P.P.
        • Janson C.
        • Norrman E.
        • et al.
        Onset and remission of allergic rhinitis and asthma and the relationship with atopic sensitization and smoking.
        Am J Respir Crit Care Med. 2000; 162: 920-924
        • Sazonov Kocevar V.
        • Thomas 3rd, J.
        • Jonsson L.
        • et al.
        Association between allergic rhinitis and hospital resource use among asthmatic children in Norway.
        Allergy. 2005; 60: 338-342
        • Leger D.
        • Annesi-Maesano I.
        • Carat F.
        • et al.
        Allergic rhinitis and its consequences on quality of sleep: An unexplored area.
        Arch Intern Med. 2006; 166: 1744-1748
        • Izuhara Y.
        • Matsumoto H.
        • Nagasaki T.
        • et al.
        Mouth breathing, another risk factor for asthma: the Nagahama Study.
        Allergy. 2016; 71: 1031-1036
        • Boulet L.P.
        Asymptomatic airway hyperresponsiveness: a curiosity or an opportunity to prevent asthma?.
        Am J Respir Crit Care Med. 2003; 167: 371-378
        • Braman S.S.
        • Barrows A.A.
        • DeCotiis B.A.
        • et al.
        Airway hyperresponsiveness in allergic rhinitis. A risk factor for asthma.
        Chest. 1987; 91: 671-674
        • Greisner 3rd, W.A.
        • Settipane R.J.
        • Settipane G.A.
        Co-existence of asthma and allergic rhinitis: a 23-year follow-up study of college students.
        Allergy Asthma Proc. 1998; 19: 185-188
        • Bousquet J.
        • Van Cauwenberge P.
        • Khaltaev N.
        • et al.
        Allergic rhinitis and its impact on asthma.
        J Allergy Clin Immunol. 2001; 108: S147-S334
        • Bousquet J.
        • Gaugris S.
        • Kocevar V.S.
        • et al.
        Increased risk of asthma attacks and emergency visits among asthma patients with allergic rhinitis: a subgroup analysis of the investigation of montelukast as a partner agent for complementary therapy [corrected].
        Clin Exp Allergy. 2005; 35: 723-727
        • Bjermer L.
        • Bisgaard H.
        • Bousquet J.
        • et al.
        Montelukast and fluticasone compared with salmeterol and fluticasone in protecting against asthma exacerbation in adults: one year, double blind, randomised, comparative trial.
        BMJ. 2003; 327: 891
        • Lohia S.
        • Schlosser R.J.
        • Soler Z.M.
        Impact of intranasal corticosteroids on asthma outcomes in allergic rhinitis: a meta-analysis.
        Allergy. 2013; 68: 569-579
        • Wise S.K.
        • Lin S.Y.
        • Toskala E.
        • et al.
        International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis.
        Int Forum Allergy Rhinol. 2018; 8: 108-352
        • Aaronson D.W.
        Evaluation of cetirizine in patients with allergic rhinitis and perennial asthma.
        Ann Allergy Asthma Immunol. 1996; 76: 440-446
        • Aubier M.
        • Neukirch C.
        • Peiffer C.
        • et al.
        Effect of cetirizine on bronchial hyperresponsiveness in patients with seasonal allergic rhinitis and asthma.
        Allergy. 2001; 56: 35-42
        • Grant J.A.
        • Nicodemus C.F.
        • Findlay S.R.
        • et al.
        Cetirizine in patients with seasonal rhinitis and concomitant asthma: prospective, randomized, placebo-controlled trial.
        J Allergy Clin Immunol. 1995; 95: 923-932
        • Kim H.
        • Bouchard J.
        • Renzi P.M.
        The link between allergic rhinitis and asthma: a role for antileukotrienes?.
        Can Respir J. 2008; 15: 91-98
        • Hox V.
        • Lourijsen E.
        • Jordens A.
        • et al.
        Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper.
        Clin Transl Allergy. 2020; 10: 1
        • Normansell R.
        • Kew K.M.
        • Mansour G.
        Different oral corticosteroid regimens for acute asthma.
        Cochrane Database Syst Rev. 2016; 5: CD011801
        • Marogna M.
        • Spadolini I.
        • Massolo A.
        • et al.
        Long-lasting effects of sublingual immunotherapy according to its duration: a 15-year prospective study.
        J Allergy Clin Immunol. 2010; 126: 969-975
        • Edwards T.S.
        • Wise S.K.
        Clinical Applications of Sublingual Immunotherapy.
        Otolaryngol Clin North Am. 2017; 50: 1121-1134
        • Corren J.
        • Casale T.
        • Deniz Y.
        • et al.
        Omalizumab, a recombinant humanized anti-IgE antibody, reduces asthma-related emergency room visits and hospitalizations in patients with allergic asthma.
        J Allergy Clin Immunol. 2003; 111: 87-90
        • Holgate S.T.
        • Djukanovic R.
        • Casale T.
        • et al.
        Anti-immunoglobulin E treatment with omalizumab in allergic diseases: an update on anti-inflammatory activity and clinical efficacy.
        Clin Exp Allergy. 2005; 35: 408-416
        • Vignola A.M.
        • Humbert M.
        • Bousquet J.
        • et al.
        Efficacy and tolerability of anti-immunoglobulin E therapy with omalizumab in patients with concomitant allergic asthma and persistent allergic rhinitis: SOLAR.
        Allergy. 2004; 59: 709-717
        • Settipane G.A.
        • Klein D.E.
        Non allergic rhinitis: demography of eosinophils in nasal smear, blood total eosinophil counts and IgE levels.
        N Engl Reg Allergy Proc. 1985; 6: 363-366
        • Moneret-Vautrin D.A.
        • Hsieh V.
        • Wayoff M.
        • et al.
        Nonallergic rhinitis with eosinophilia syndrome a precursor of the triad: nasal polyposis, intrinsic asthma, and intolerance to aspirin.
        Ann Allergy. 1990; 64: 513-518
        • Ellis A.K.
        • Keith P.K.
        Nonallergic rhinitis with eosinophilia syndrome.
        Curr Allergy Asthma Rep. 2006; 6: 215-220
        • Meng Y.
        • Yan B.
        • Wang Y.
        • et al.
        Diagnosis and management of nonallergic rhinitis with eosinophilia syndrome using cystatin SN together with symptoms.
        World Allergy Organ J. 2020; 13: 100134
        • De Corso E.
        • Anzivino R.
        • Galli J.
        • et al.
        Antileukotrienes improve naso-ocular symptoms and biomarkers in patients with NARES and asthma.
        Laryngoscope. 2019; 129: 551-557
        • Bousquet J.
        • Khaltaev N.
        • Cruz A.A.
        • et al.
        Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen).
        Allergy. 2008; 63: 8-160
        • De Corso E.
        • Seccia V.
        • Ottaviano G.
        • et al.
        Clinical Evidence of Type 2 Inflammation in Non-allergic Rhinitis with Eosinophilia Syndrome: a Systematic Review.
        Curr Allergy Asthma Rep. 2022; 22: 29-42
        • Crisci C.D.
        • Ardusso L.R.F.
        A Precision Medicine Approach to Rhinitis Evaluation and Management.
        Curr Treat Options Allergy. 2020; 7: 93-109
        • Purello-D'Ambrosio F.
        • Isola S.
        • Ricciardi L.
        • et al.
        A controlled study on the effectiveness of loratadine in combination with flunisolide in the treatment of nonallergic rhinitis with eosinophilia (NARES).
        Clin Exp Allergy. 1999; 29: 1143-1147
        • Mygind N.
        Effects of corticosteroid therapy in non-allergic rhinosinusitis.
        Acta Otolaryngol. 1996; 116: 164-166
        • Langdon C.
        • Mullol J.
        Nasal polyps in patients with asthma: prevalence, impact, and management challenges.
        J Asthma Allergy. 2016; 9: 45-53
        • Tint D.
        • Kubala S.
        • Toskala E.
        Risk Factors and Comorbidities in Chronic Rhinosinusitis.
        Curr Allergy Asthma Rep. 2016; 16: 16
        • Bilodeau L.
        • Boulay M.E.
        • Prince P.
        • et al.
        Comparative clinical and airway inflammatory features of asthmatics with or without polyps.
        Rhinology. 2010; 48: 420-425
        • Lehrer E.
        • Mullol J.
        • Agredo F.
        • et al.
        Management of chronic rhinosinusitis in asthma patients: is there still a debate?.
        Curr Allergy Asthma Rep. 2014; 14: 440
        • Yoshimura K.
        • Kawata R.
        • Haruna S.
        • et al.
        Clinical epidemiological study of 553 patients with chronic rhinosinusitis in Japan.
        Allergol Int. 2011; 60: 491-496
        • Lund V.J.
        The effect of sinonasal surgery on asthma.
        Allergy. 1999; 54: 141-145
        • Scadding G.
        The effect of medical treatment of sinusitis upon concomitant asthma.
        Allergy. 1999; 54: 136-140
        • Ragab S.M.
        • Lund V.J.
        • Scadding G.
        Evaluation of the medical and surgical treatment of chronic rhinosinusitis: a prospective, randomised, controlled trial.
        Laryngoscope. 2004; 114: 923-930
        • Schaper C.
        • Noga O.
        • Koch B.
        • et al.
        Anti-inflammatory properties of montelukast, a leukotriene receptor antagonist in patients with asthma and nasal polyposis.
        J Investig Allergol Clin Immunol. 2011; 21: 51-58
        • Fokkens W.J.
        • Lund V.J.
        • Hopkins C.
        • et al.
        European Position Paper on Rhinosinusitis and Nasal Polyps 2020.
        Rhinology. 2020; 58: 1-464
        • De Schryver E.
        • Derycke L.
        • Calus L.
        • et al.
        The effect of systemic treatments on periostin expression reflects their interference with the eosinophilic inflammation in chronic rhinosinusitis with nasal polyps.
        Rhinology. 2017; 55: 152-160
        • Izuhara K.
        • Ohta S.
        • Ono J.
        Using Periostin as a Biomarker in the Treatment of Asthma.
        Allergy Asthma Immunol Res. 2016; 8: 491-498
        • Smith T.L.
        • Mendolia-Loffredo S.
        • Loehrl T.A.
        • et al.
        Predictive factors and outcomes in endoscopic sinus surgery for chronic rhinosinusitis.
        Laryngoscope. 2005; 115: 2199-2205
        • Uri N.
        • Cohen-Kerem R.
        • Barzilai G.
        • et al.
        Functional endoscopic sinus surgery in the treatment of massive polyposis in asthmatic patients.
        J Laryngol Otol. 2002; 116: 185-189
        • Awad O.G.
        • Fasano M.B.
        • Lee J.H.
        • et al.
        Asthma outcomes after endoscopic sinus surgery in aspirin-tolerant versus aspirin-induced asthmatic patients.
        Am J Rhinol. 2008; 22: 197-203
        • Awad O.G.
        • Lee J.H.
        • Fasano M.B.
        • et al.
        Sinonasal outcomes after endoscopic sinus surgery in asthmatic patients with nasal polyps: a difference between aspirin-tolerant and aspirin-induced asthma?.
        Laryngoscope. 2008; 118: 1282-1286
        • Benninger M.S.
        • Sindwani R.
        • Holy C.E.
        • et al.
        Impact of medically recalcitrant chronic rhinosinusitis on incidence of asthma.
        Int Forum Allergy Rhinol. 2016; 6: 124-129
        • Leung T.N.
        • Lam P.M.
        • Ng P.C.
        • et al.
        Repeated courses of antenatal corticosteroids: is it justified?.
        Acta Obstet Gynecol Scand. 2003; 82: 589-596
        • Rix I.
        • Hakansson K.
        • Larsen C.G.
        • et al.
        Management of chronic rhinosinusitis with nasal polyps and coexisting asthma: A systematic review.
        Am J Rhinol Allergy. 2015; 29: 193-201
        • Samter M.
        • Beers Jr., R.F.
        Intolerance to aspirin. Clinical studies and consideration of its pathogenesis.
        Ann Intern Med. 1968; 68: 975-983
        • Laidlaw T.M.
        Pathogenesis of NSAID-induced reactions in aspirin-exacerbated respiratory disease.
        World J Otorhinolaryngol Head Neck Surg. 2018; 4: 162-168
        • Mascia K.
        • Haselkorn T.
        • Deniz Y.M.
        • et al.
        Aspirin sensitivity and severity of asthma: evidence for irreversible airway obstruction in patients with severe or difficult-to-treat asthma.
        J Allergy Clin Immunol. 2005; 116: 970-975
        • Marcus S.
        • Schertzer J.
        • Roland L.T.
        • et al.
        Central compartment atopic disease: prevalence of allergy and asthma compared with other subtypes of chronic rhinosinusitis with nasal polyps.
        Int Forum Allergy Rhinol. 2020; 10: 183-189
        • Rajan J.P.
        • Wineinger N.E.
        • Stevenson D.D.
        • et al.
        Prevalence of aspirin-exacerbated respiratory disease among asthmatic patients: A meta-analysis of the literature.
        J Allergy Clin Immunol. 2015; 135: 676-681 e671
        • Fahrenholz J.M.
        Natural history and clinical features of aspirin-exacerbated respiratory disease.
        Clin Rev Allergy Immunol. 2003; 24: 113-124
        • Dahlen S.E.
        • Malmstrom K.
        • Nizankowska E.
        • et al.
        Improvement of aspirin-intolerant asthma by montelukast, a leukotriene antagonist: a randomized, double-blind, placebo-controlled trial.
        Am J Respir Crit Care Med. 2002; 165: 9-14
        • Dahlen B.
        • Nizankowska E.
        • Szczeklik A.
        • et al.
        Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin-intolerant asthmatics.
        Am J Respir Crit Care Med. 1998; 157: 1187-1194
        • Bachert C.
        • Han J.K.
        • Desrosiers M.
        • et al.
        Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials.
        Lancet. 2019; 394: 1638-1650
        • Laidlaw T.M.
        • Bachert C.
        • Amin N.
        • et al.
        Dupilumab improves upper and lower airway disease control in chronic rhinosinusitis with nasal polyps and asthma.
        Ann Allergy Asthma Immunol. 2021; 126: 584-592 e581
        • Loehrl T.A.
        • Ferre R.M.
        • Toohill R.J.
        • et al.
        Long-term asthma outcomes after endoscopic sinus surgery in aspirin triad patients.
        Am J Otol. 2006; 27: 154-160
        • DeGregorio G.A.
        • Singer J.
        • Cahill K.N.
        • et al.
        A 1-Day, 90-Minute Aspirin Challenge and Desensitization Protocol in Aspirin-Exacerbated Respiratory Disease.
        J Allergy Clin Immunol Pract. 2019; 7: 1174-1180
        • Chaaban M.R.
        • Moffatt D.
        • Wright A.E.
        • et al.
        Meta-analysis Exploring Sinopulmonary Outcomes of Aspirin Desensitization in Aspirin-Exacerbated Respiratory Disease.
        Otolaryngol Head Neck Surg. 2021; 164: 11-18
        • Stevens W.W.
        • Jerschow E.
        • Baptist A.P.
        • et al.
        The role of aspirin desensitization followed by oral aspirin therapy in managing patients with aspirin-exacerbated respiratory disease: A Work Group Report from the Rhinitis, Rhinosinusitis and Ocular Allergy Committee of the American Academy of Allergy, Asthma & Immunology.
        J Allergy Clin Immunol. 2021; 147: 827-844
        • Fruth K.
        • Pogorzelski B.
        • Schmidtmann I.
        • et al.
        Low-dose aspirin desensitization in individuals with aspirin-exacerbated respiratory disease.
        Allergy. 2013; 68: 659-665
        • Cho S.H.
        • Hamilos D.L.
        • Han D.H.
        • et al.
        Phenotypes of Chronic Rhinosinusitis.
        J Allergy Clin Immunol Pract. 2020; 8: 1505-1511
        • Ma C.
        • Mehta N.K.
        • Nguyen S.A.
        • et al.
        Demographic Variation in Chronic Rhinosinusitis by Subtype and Region: A Systematic Review.
        Am J Rhinol Allergy. 2022; 36: 367-377
        • Bent 3rd, J.P.
        • Kuhn F.A.
        Diagnosis of allergic fungal sinusitis.
        Otolaryngol Head Neck Surg. 1994; 111: 580-588
        • Ryan M.W.
        • Clark C.M.
        Allergic Fungal Rhinosinusitis and the Unified Airway: the Role of Antifungal Therapy in AFRS.
        Curr Allergy Asthma Rep. 2015; 15: 75
        • Cody 2nd, D.T.
        • Neel 3rd, H.B.
        • Ferreiro J.A.
        • et al.
        Allergic fungal sinusitis: the Mayo Clinic experience.
        Laryngoscope. 1994; 104: 1074-1079
        • Manning S.C.
        • Holman M.
        Further evidence for allergic pathophysiology in allergic fungal sinusitis.
        Laryngoscope. 1998; 108: 1485-1496
        • Philpott C.M.
        • Erskine S.
        • Hopkins C.
        • et al.
        Prevalence of asthma, aspirin sensitivity and allergy in chronic rhinosinusitis: data from the UK National Chronic Rhinosinusitis Epidemiology Study.
        Respir Res. 2018; 19: 129
        • Barac A.
        • Stevanovic G.
        • Pekmezovic M.
        • et al.
        Study toward resolving the controversy over the definition of allergic fungal rhinosinusitis.
        Med Mycol. 2018; 56: 162-171
        • Glass D.
        • Amedee R.G.
        Allergic fungal rhinosinusitis: a review.
        Ochsner J. 2011; 11: 271-275
        • Rupa V.
        • Jacob M.
        • Mathews M.S.
        • et al.
        A prospective, randomised, placebo-controlled trial of postoperative oral steroid in allergic fungal sinusitis.
        Eur Arch Otorhinolaryngol. 2010; 267: 233-238
        • Bassichis B.A.
        • Marple B.F.
        • Mabry R.L.
        • et al.
        Use of immunotherapy in previously treated patients with allergic fungal sinusitis.
        Otolaryngol Head Neck Surg. 2001; 125: 487-490
        • Gan E.C.
        • Thamboo A.
        • Rudmik L.
        • et al.
        Medical management of allergic fungal rhinosinusitis following endoscopic sinus surgery: an evidence-based review and recommendations.
        Int Forum Allergy Rhinol. 2014; 4: 702-715
        • Schubert M.S.
        Antileukotriene therapy for allergic fungal sinusitis.
        J Allergy Clin Immunol. 2001; 108: 466-467
        • Gan E.C.
        • Habib A.R.
        • Rajwani A.
        • et al.
        Omalizumab therapy for refractory allergic fungal rhinosinusitis patients with moderate or severe asthma.
        Am J Otolaryngol. 2015; 36: 672-677
        • Karp J.
        • Dhillon I.
        • Panchmatia R.
        • et al.
        Subcutaneous Mepolizumab Injection: An Adjunctive Treatment for Recalcitrant Allergic Fungal Rhinosinusitis Patients With Asthma.
        Am J Rhinol Allergy. 2021; 35: 256-263
        • DelGaudio J.M.
        • Loftus P.A.
        • Hamizan A.W.
        • et al.
        Central compartment atopic disease.
        Am J Rhinol Allergy. 2017; 31: 228-234
        • Kong W.
        • Wu Q.
        • Chen Y.
        • et al.
        Chinese Central Compartment Atopic Disease: The Clinical Characteristics and Cellular Endotypes Based on Whole-Slide Imaging.
        J Asthma Allergy. 2022; 15: 341-352
        • Shih L.C.
        • Hsieh B.H.
        • Ma J.H.
        • et al.
        A comparison of central compartment atopic disease and lateral dominant nasal polyps.
        Int Forum Allergy Rhinol. 2022; https://doi.org/10.1002/alr.22996
        • DelGaudio J.M.
        Central compartment atopic disease: the missing link in the allergy and chronic rhinosinusitis with nasal polyps saga.
        Int Forum Allergy Rhinol. 2020; 10: 1191-1192
        • Lee K.
        • Kim T.H.
        • Lee S.H.
        • et al.
        Predictive Value of Radiologic Central Compartment Atopic Disease for Identifying Allergy and Asthma in Pediatric Patients.
        Ear Nose Throat J. 2021; (145561321997546)https://doi.org/10.1177/0145561321997546
        • Steehler A.J.
        • Vuncannon J.R.
        • Wise S.K.
        • et al.
        Central compartment atopic disease: outcomes compared with other subtypes of chronic rhinosinusitis with nasal polyps.
        Int Forum Allergy Rhinol. 2021; 11: 1549-1556
        • Ferguson B.J.
        Eosinophilic mucin rhinosinusitis: a distinct clinicopathological entity.
        Laryngoscope. 2000; 110: 799-813
        • Uri N.
        • Ronen O.
        • Marshak T.
        • et al.
        Allergic fungal sinusitis and eosinophilic mucin rhinosinusitis: diagnostic criteria.
        J Laryngol Otol. 2013; 127: 867-871
        • Ramadan H.H.
        • Quraishi H.A.
        Allergic mucin sinusitis without fungus.
        Am J Rhinol. 1997; 11: 145-147
        • Ghorbani J.
        • Hosseini Vajari A.
        • Pourdowlat G.
        • et al.
        Eosinophilic Mucin Rhinosinusitis in Iranian Patients Undergoing Endoscopic Sinus Surgery.
        Iran J Otorhinolaryngol. 2018; 30: 347-353
        • Park S.K.
        • Park K.W.
        • Mo J.H.
        • et al.
        Clinicopathological and Radiological Features of Chronic Rhinosinusitis with Eosinophilic Mucin in Chungcheong Province of Korea.
        Mycopathologia. 2019; 184: 423-431