Advertisement

Sex Differences in Airway Diseases

Published:October 17, 2022DOI:https://doi.org/10.1016/j.otc.2022.09.004

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.

      Content published before 2002 is available via pay-per-view purchase only.

      Subscribe:

      Subscribe to Otolaryngologic Clinics of North America
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Mauvais-Jarvis F.
        • Bairey Merz N.
        • Barnes P.J.
        • et al.
        Sex and gender: modifiers of health, disease, and medicine.
        Lancet. 2020; 396: 565-582
        • Akinbami L.J.
        • Liu X.
        Chronic obstructive pulmonary disease among adults aged 18 and over in the United States, 1998-2009.
        NCHS Data Brief. 2011; : 1-8
        • Akinbami L.J.
        • Moorman J.E.
        • Bailey C.
        • et al.
        Trends in asthma prevalence, health care use, and mortality in the United States, 2001-2010.
        NCHS Data Brief. 2012; : 1-8
        • Salvi S.S.
        • Barnes P.J.
        Chronic obstructive pulmonary disease in non-smokers.
        Lancet. 2009; 374: 733-743
        • Ference E.H.
        • Tan B.K.
        • Hulse K.E.
        • et al.
        Commentary on gender differences in prevalence, treatment, and quality of life of patients with chronic rhinosinusitis.
        Allergy Rhinol (Providence). 2015; 6: 82-88
        • Bartosik T.J.
        • Liu D.T.
        • Campion N.J.
        • et al.
        Differences in men and women suffering from CRSwNP and AERD in quality of life.
        Eur Arch Otorhinolaryngol. 2021; 278: 1419-1427
        • Lal D.
        • Rounds A.B.
        • Divekar R.
        Gender-specific differences in chronic rhinosinusitis patients electing endoscopic sinus surgery.
        Int Forum Allergy Rhinol. 2016; 6: 278-286
        • Ramos L.
        • Massey C.J.
        • Asokan A.
        • et al.
        Examination of sex differences in a chronic rhinosinusitis surgical cohort.
        Otolaryngol Head Neck Surg. 2022; (1945998221076468)https://doi.org/10.1177/01945998221076468
        • Fuseini H.
        • Newcomb D.C.
        Mechanisms driving gender differences in asthma.
        Curr Allergy Asthma Rep. 2017; 17: 19
        • Lam G.Y.
        • Goodwin J.
        • Wilcox P.G.
        • et al.
        Sex disparities in cystic fibrosis: review on the effect of female sex hormones on lung pathophysiology and outcomes.
        ERJ Open Res. 2021; 7https://doi.org/10.1183/23120541.00475-2020
        • Becklake M.R.
        • Kauffmann F.
        Gender differences in airway behaviour over the human life span.
        Thorax. 1999; 54: 1119-1138
        • Harness-Brumley C.L.
        • Elliott A.C.
        • Rosenbluth D.B.
        • et al.
        Gender differences in outcomes of patients with cystic fibrosis.
        J Womens Health (Larchmt). 2014; 23: 1012-1020
        • Mendolia-Loffredo S.
        • Laud P.W.
        • Sparapani R.
        • et al.
        Sex differences in outcomes of sinus surgery.
        Laryngoscope. 2006; 116: 1199-1203
        • Perkins K.A.
        • Scott J.
        Sex differences in long-term smoking cessation rates due to nicotine patch.
        Nicotine Tob Res. 2008; 10: 1245-1250https://doi.org/10.1080/14622200802097506
        • Aryal S.
        • Diaz-Guzman E.
        • Mannino D.M.
        COPD and gender differences: an update.
        Transl Res. 2013; 162: 208-218
        • Rosenfeld M.
        • Davis R.
        • FitzSimmons S.
        • et al.
        Gender gap in cystic fibrosis mortality.
        Am J Epidemiol. 1997; 145: 794-803
        • Raghavan D.
        • Jain R.
        Increasing awareness of sex differences in airway diseases.
        Respirology. 2016; 21: 449-459
        • Naumova A.K.
        • Al Tuwaijri A.
        • Morin A.
        • et al.
        Sex- and age-dependent DNA methylation at the 17q12-q21 locus associated with childhood asthma.
        Hum Genet. 2013; 132: 811-822
        • National Center for Health Statistics
        Crude percentages of sinusitis for adults aged 18 and over, United States, 2015-2018. National Health Interview Survey.
        (Available at:) (Accessed May 19 2022)
        • Lal D.
        • Golisch K.B.
        • Elwell Z.A.
        • et al.
        Gender-specific analysis of outcomes from endoscopic sinus surgery for chronic rhinosinusitis.
        Int Forum Allergy Rhinol. 2016; 6: 896-905
        • Whitley H.
        • Lindsey W.
        Sex-based differences in drug activity.
        Am Fam Physician. 2009; 80: 1254-1258
        • Duma D.
        • Collins J.B.
        • Chou J.W.
        • et al.
        Sexually dimorphic actions of glucocorticoids provide a link to inflammatory diseases with gender differences in prevalence.
        Sci Signal. 2010; 3: ra74
        • Bhattacharyya N.
        • Wasan A.
        Do anxiety and depression confound symptom reporting and diagnostic accuracy in chronic rhinosinusitis?.
        Ann Otol Rhinol Laryngol. 2008; 117: 18-23
        • Centers for Disease Control
        Most recent national asthma data.
        (Available at) (Accessed May 22, 2022)
        • Mead J.
        Dysanapsis in normal lungs assessed by the relationship between maximal flow, static recoil, and vital capacity.
        Am Rev Respir Dis. 1980; 121: 339-342
        • DeGroodt E.
        • van Pelt W.
        • Borsboom G.
        • et al.
        Growth of lung and thorax dimensions during the pubertal growth spurt.
        Eur Respir J. 1988; 1: 102-108
        • Dijkstra A.
        • Vonk J.M.
        • Jongepier H.
        • et al.
        Lung function decline in asthma: association with inhaled corticosteroids, smoking and sex.
        Thorax. 2006; 61: 105-110
        • Convery R.P.
        • Leitch D.N.
        • Bromly C.
        • et al.
        Effect of inhaled fluticasone propionate on airway responsiveness in treatment-naive individuals--a lesser benefit in females.
        Eur Respir J. 2000; 15: 19-24
        • Goodman D.E.
        • Israel E.
        • Rosenberg M.
        • et al.
        The influence of age, diagnosis, and gender on proper use of metered-dose inhalers.
        Am J Respir Crit Care Med. 1994; 150: 1256-1261
        • Hayton C.
        • Clark A.
        • Olive S.
        • et al.
        Barriers to pulmonary rehabilitation: characteristics that predict patient attendance and adherence.
        Respir Med. 2013; 107: 401-407
        • Mannino D.M.
        • Homa D.M.
        • Akinbami L.J.
        • et al.
        Chronic obstructive pulmonary disease surveillance--United States, 1971-2000.
        MMWR Surveill Summ. 2002; 51: 1-16
        • Sorheim I.C.
        • Johannessen A.
        • Gulsvik A.
        • et al.
        Gender differences in COPD: are women more susceptible to smoking effects than men?.
        Thorax. 2010; 65: 480-485
        • Son D.-S.
        • Roby K.F.
        • Rozman K.K.
        • et al.
        Estradiol enhances and estriol inhibits the expression of CYP1A1 induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in a mouse ovarian cancer cell line.
        Toxicology. 2002; 176: 229-243
        • Dempsey D.
        • Jacob 3rd, P.
        • Benowitz N.L.
        Accelerated metabolism of nicotine and cotinine in pregnant smokers.
        J Pharmacol Exp Ther. 2002; 301: 594-598
        • Allen S.S.
        • Bade T.
        • Center B.
        • et al.
        Menstrual phase effects on smoking relapse.
        Addiction. 2008; 103: 809-821
        • Perkins K.A.
        • Marcus M.D.
        • Levine M.D.
        • et al.
        Cognitive-behavioral therapy to reduce weight concerns improves smoking cessation outcome in weight-concerned women.
        J Consult Clin Psychol. 2001; 69: 604-613
        • Celli B.R.
        • Cote C.G.
        • Marin J.M.
        • et al.
        The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease.
        N Engl J Med. 2004; 350: 1005-1012
        • Di Marco F.
        • Verga M.
        • Reggente M.
        • et al.
        Anxiety and depression in COPD patients: The roles of gender and disease severity.
        Respir Med. 2006; 100: 1767-1774
        • Chotirmall S.H.
        • Greene C.M.
        • Oglesby I.K.
        • et al.
        17Beta-estradiol inhibits IL-8 in cystic fibrosis by up-regulating secretory leucoprotease inhibitor.
        Am J Respir Crit Care Med. 2010; 182: 62-72
        • Mirsaeidi M.
        • Machado R.F.
        • Garcia J.G.
        • et al.
        Nontuberculous mycobacterial disease mortality in the United States, 1999-2010: a population-based comparative study.
        PLoS One. 2014; 9: e91879
        • Kim R.D.
        • Greenberg D.E.
        • Ehrmantraut M.E.
        • et al.
        Pulmonary nontuberculous mycobacterial disease: prospective study of a distinct preexisting syndrome.
        Am J Respir Crit Care Med. 2008; 178: 1066-1074
        • Han M.K.
        • Postma D.
        • Mannino D.M.
        • et al.
        Gender and chronic obstructive pulmonary disease: why it matters.
        Am J Respir Crit Care Med. 2007; 176: 1179-1184